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TitleCrystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 77, Page 486-495, Year 2021
Publish dateJun 15, 2020 (structure data deposition date)
AuthorsYang, J.Y. / Halmo, S.M. / Praissman, J. / Chapla, D. / Singh, D. / Wells, L. / Moremen, K.W. / Lanzilotta, W.N.
External linksActa Crystallogr D Struct Biol / PubMed:33825709
MethodsX-ray diffraction
Resolution2 - 2.57 Å
Structure data

PDB-6xfi:
Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6xi2:
Apo form of POMGNT2
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / muscular dystrophy / alpha-dystroglycan / O-mannosylation / POMGNT2 / muscular dystrophy; alpha-dystroglycan; O-mannosylation; POMGNT2

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