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-Structure paper
Title | Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 16, Page 740-752, Year 2021 |
Publish date | Oct 19, 2020 (structure data deposition date) |
Authors | Taylor, I.R. / Paczkowski, J.E. / Jeffrey, P.D. / Henke, B.R. / Smith, C.D. / Bassler, B.L. |
External links | Acs Chem. Biol. / PubMed:33793200 |
Methods | X-ray diffraction |
Resolution | 1.99 - 2 Å |
Structure data | PDB-7kgw: PDB-7kgx: |
Chemicals | ChemComp-FE: ChemComp-WDY: ChemComp-HOH: ChemComp-WE1: |
Source |
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Keywords | HYDROLASE/Inhibitor / Quorum Sensing / PQS / PqsE / inhibitor / Metal Binding Protein / HYDROLASE-Inhibitor complex |