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TitleA chemical genetics approach to examine the functions of AAA proteins.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 28, Page 388-397, Year 2021
Publish dateJan 5, 2021 (structure data deposition date)
AuthorsCupido, T. / Jones, N.H. / Grasso, M.J. / Pisa, R. / Kapoor, T.M.
External linksNat. Struct. Mol. Biol. / PubMed:33782614
MethodsX-ray diffraction
Resolution2.81 Å
Structure data

PDB-7l9x:
Structure of VPS4B in complex with an allele-specific covalent inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

Chemicals

ChemComp-XQV:
N-{3-[(8-phenyl[1,2,4]triazolo[1,5-a]pyridin-2-yl)amino]phenyl}propanamide

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / chemical Inhibitor / hydrolase / ATPase / AAA superfamily

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