+Search query
-Structure paper
Title | Hinge-shift mechanism as a protein design principle for the evolution of beta-lactamases from substrate promiscuity to specificity. |
---|---|
Journal, issue, pages | Nat Commun, Vol. 12, Page 1852-1852, Year 2021 |
Publish date | Apr 20, 2020 (structure data deposition date) |
![]() | Modi, T. / Risso, V.A. / Martinez-Rodriguez, S. / Gavira, J.A. / Mebrat, M.D. / Van Horn, W.D. / Sanchez-Ruiz, J.M. / Banu Ozkan, S. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | ![]() PDB-6yrs: |
Chemicals | ![]() ChemComp-ACT: ![]() ChemComp-PGE: ![]() ChemComp-EDO: ![]() ChemComp-SO4: ![]() ChemComp-PEG: ![]() ChemComp-HOH: |
Source |
|
![]() | HYDROLASE / ANTIBIOTIC RESISTANCE / ANCESTRAL RECONSTRUCTED |