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TitleBiosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Journal, issue, pagesMol Biotechnol., Vol. 63, Page 502-514, Year 2021
Publish dateJan 12, 2021 (structure data deposition date)
AuthorsAlali, A. / Zhang, L. / Li, J. / Zuo, C. / Wassouf, D. / Yan, X. / Schwarzer, P. / Gunther, S. / Einsle, O. / Bechthold, A.
External linksMol Biotechnol. / PubMed:33763824
MethodsX-ray diffraction
Resolution1.6 - 1.795 Å
Structure data

PDB-7bio:
Crystal structure of monooxygenase RslO4 from Streptomyces bottropensis
Method: X-RAY DIFFRACTION / Resolution: 1.795 Å

PDB-7bip:
Crystal structure of monooxygenase RslO1 from Streptomyces bottropensis
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-EOH:
ETHANOL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-XPE:
3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL / precipitant*YM

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

Source
  • streptomyces bottropensis (bacteria)
KeywordsOXIDOREDUCTASE / Rishirilides biosynthesis

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