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TitleDevelopment of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4- b ]furan Nucleoside Analogues.
Journal, issue, pagesJ. Org. Chem., Vol. 86, Page 5142-5151, Year 2021
Publish dateDec 14, 2020 (structure data deposition date)
AuthorsCandito, D.A. / Ye, Y. / Quiroz, R.V. / Reutershan, M.H. / Witter, D. / Gadamsetty, S.B. / Li, H. / Sauri, J. / Schneider, S.E. / Lam, Y.H. / Palte, R.L.
External linksJ. Org. Chem. / PubMed:33755465
MethodsX-ray diffraction
Resolution2.47 Å
Structure data

PDB-7l1g:
PRMT5-MEP50 Complexed with SAM
Method: X-RAY DIFFRACTION / Resolution: 2.47 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / methyltransferase

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