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TitleStructural and functional insights into esterase-mediated macrolide resistance.
Journal, issue, pagesNat Commun, Vol. 12, Page 1732-1732, Year 2021
Publish dateJun 9, 2020 (structure data deposition date)
AuthorsZielinski, M. / Park, J. / Sleno, B. / Berghuis, A.M.
External linksNat Commun / PubMed:33741980
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-6xcq:
Erythromycin esterase EreC, mutant H289N in its closed conformation
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6xcs:
Erythromycin esterase mutant EreC H289N in its open conformation
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-PGO:
S-1,2-PROPANEDIOL

ChemComp-HOH:
WATER

Source
  • klebsiella pneumoniae (bacteria)
KeywordsHYDROLASE / Macrolide / esterase

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