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TitleOptimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Journal, issue, pagesSci Adv, Vol. 7, Year 2021
Publish dateJul 22, 2020 (structure data deposition date)
AuthorsMbianda, J. / Bakail, M. / Andre, C. / Moal, G. / Perrin, M.E. / Pinna, G. / Guerois, R. / Becher, F. / Legrand, P. / Traore, S. ...Mbianda, J. / Bakail, M. / Andre, C. / Moal, G. / Perrin, M.E. / Pinna, G. / Guerois, R. / Becher, F. / Legrand, P. / Traore, S. / Douat, C. / Guichard, G. / Ochsenbein, F.
External linksSci Adv / PubMed:33741589
MethodsX-ray diffraction
Resolution1.798 Å
Structure data

PDB-6zuf:
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Method: X-RAY DIFFRACTION / Resolution: 1.798 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCHAPERONE / Histone chaperone Rational design Peptidomimetics Foldamers

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