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-Structure paper
Title | Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 216, Page 113309-113309, Year 2021 |
Publish date | Sep 11, 2020 (structure data deposition date) |
![]() | Jansa, J. / Jorda, R. / Skerlova, J. / Pachl, P. / Perina, M. / Reznickova, E. / Heger, T. / Gucky, T. / Rezacova, P. / Lycka, A. / Krystof, V. |
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Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | ![]() PDB-7ack: |
Chemicals | ![]() ChemComp-R7B: ![]() ChemComp-EDO: ![]() ChemComp-NA: ![]() ChemComp-NO3: ![]() ChemComp-HOH: |
Source |
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![]() | CELL CYCLE / cyclin-dependent kinase 2 / substituted imidazo[1 / 2-c]pyrimidin-5-one / inhibitor |