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| Title | The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract. |
|---|---|
| Journal, issue, pages | Emerg Microbes Infect, Vol. 10, Page 481-492, Year 2021 |
| Publish date | Jun 13, 2020 (structure data deposition date) |
Authors | Shi, Y. / Shuai, L. / Wen, Z. / Wang, C. / Yan, Y. / Jiao, Z. / Guo, F. / Fu, Z.F. / Chen, H. / Bu, Z. / Peng, G. |
External links | Emerg Microbes Infect / PubMed:33691601 |
| Methods | X-ray diffraction |
| Resolution | 2.346 Å |
| Structure data | ![]() PDB-7cbt: |
| Chemicals | ![]() ChemComp-K36: ![]() ChemComp-HOH: |
| Source |
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Keywords | VIRAL PROTEIN / SARS-CoV-2 / main protease / GC376 / complex |
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