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TitleParallel molecular mechanisms for enzyme temperature adaptation.
Journal, issue, pagesScience, Vol. 371, Year 2021
Publish dateMay 23, 2019 (structure data deposition date)
AuthorsPinney, M.M. / Mokhtari, D.A. / Akiva, E. / Yabukarski, F. / Sanchez, D.M. / Liang, R. / Doukov, T. / Martinez, T.J. / Babbitt, P.C. / Herschlag, D.
External linksScience / PubMed:33674467
MethodsX-ray diffraction
Resolution1.251 - 1.571 Å
Structure data

PDB-6p3l:
Crystal Structure of Ketosteroid Isomerase from Mycobacterium hassiacum (mhKSI)
Method: X-RAY DIFFRACTION / Resolution: 1.571 Å

PDB-6p44:
Crystal Structure of Ketosteroid Isomerase D38N mutant from Mycobacterium hassiacum (mhKSI) bound to 3,4-dinitrophenol
Method: X-RAY DIFFRACTION / Resolution: 1.251 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GAI:
GUANIDINE

ChemComp-HOH:
WATER

ChemComp-DNX:
3,4-dinitrophenol

Source
  • mycobacterium hassiacum (strain dsm 44199 / cip 105218 / jcm 12690 / 3849) (bacteria)
KeywordsISOMERASE / Thermophile

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