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TitleBET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.
Journal, issue, pagesBiochemistry, Vol. 60, Page 648-662, Year 2021
Publish dateOct 8, 2019 (structure data deposition date)
AuthorsPatel, K. / Solomon, P.D. / Walshe, J.L. / Ford, D.J. / Wilkinson-White, L. / Payne, R.J. / Low, J.K.K. / Mackay, J.P.
External linksBiochemistry / PubMed:33620209
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-6uls:
BRD4-BD1 in complex with the a diacetylated-E2F1 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / BET / bromodomain / E2F1 / BRD4 / acetylated

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