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TitlecGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing.
Journal, issue, pagesMol. Cell, Vol. 81, Page 739-755.e7, Year 2021
Publish dateMar 3, 2020 (structure data deposition date)
AuthorsZhou, W. / Mohr, L. / Maciejowski, J. / Kranzusch, P.J.
External linksMol. Cell / PubMed:33606975
MethodsX-ray diffraction
Resolution1.80003386368 Å
Structure data

PDB-6w10:
Structure of mouse TREX1 with E198K disease-associated mutation
Method: X-RAY DIFFRACTION / Resolution: 1.80003386368 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / nuclease / DNase / innate immunity / autoimmunity

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