+Search query
-Structure paper
Title | Tricyclic-Carbocyclic ROR gamma t Inverse Agonists-Discovery of BMS-986313. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 64, Page 2714-2724, Year 2021 |
Publish date | Nov 16, 2020 (structure data deposition date) |
![]() | Yang, M.G. / Beaudoin-Bertrand, M. / Xiao, Z. / Marcoux, D. / Weigelt, C.A. / Yip, S. / Wu, D.R. / Ruzanov, M. / Sack, J.S. / Wang, J. ...Yang, M.G. / Beaudoin-Bertrand, M. / Xiao, Z. / Marcoux, D. / Weigelt, C.A. / Yip, S. / Wu, D.R. / Ruzanov, M. / Sack, J.S. / Wang, J. / Yarde, M. / Li, S. / Shuster, D.J. / Xie, J.H. / Sherry, T. / Obermeier, M.T. / Fura, A. / Stefanski, K. / Cornelius, G. / Khandelwal, P. / Karmakar, A. / Basha, M. / Babu, V. / Gupta, A.K. / Mathur, A. / Salter-Cid, L. / Denton, R. / Zhao, Q. / Dhar, T.G.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.645 Å |
Structure data | ![]() PDB-7kqj: |
Chemicals | ![]() ChemComp-Z8G: ![]() ChemComp-HOH: |
Source |
|
![]() | TRANSCRIPTION/Agonist / RORGT / NUCLEAR HORMONE RECEPTOR / LIGAND-BINDING DOMAIN / TRANSCRIPTION / TRANSCRIPTION-Agonist complex |