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TitleMechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Journal, issue, pagesSci Rep, Vol. 11, Page 3754-3754, Year 2021
Publish dateSep 3, 2020 (structure data deposition date)
AuthorsGonzalez, A. / Mannen, T. / Cagatay, T. / Fujiwara, A. / Matsumura, H. / Niesman, A.B. / Brautigam, C.A. / Chook, Y.M. / Yoshizawa, T.
External linksSci Rep / PubMed:33580145
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-7cyl:
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN/RNA BINDING PROTEIN / Nuclear import / Karyopherin / TRANSPORT PROTEIN / TRANSPORT PROTEIN-RNA BINDING PROTEIN complex

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