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Structure paper

TitleMolecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1.
Journal, issue, pagesCommun Biol, Vol. 4, Page 174-174, Year 2021
Publish dateJun 2, 2020 (structure data deposition date)
AuthorsLiu, Y. / Ma, J. / DesJarlais, R.L. / Hagan, R. / Rech, J. / Lin, D. / Liu, C. / Miller, R. / Schoellerman, J. / Luo, J. ...Liu, Y. / Ma, J. / DesJarlais, R.L. / Hagan, R. / Rech, J. / Lin, D. / Liu, C. / Miller, R. / Schoellerman, J. / Luo, J. / Letavic, M. / Grasberger, B. / Maher, M.
External linksCommun Biol / PubMed:33564124
MethodsX-ray diffraction
Resolution3.01 Å
Structure data

PDB-6x9h:
Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1)
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-UZG:
2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide

ChemComp-NA:
Unknown entry

Source
  • gallus gallus (chicken)
KeywordsTRANSPORT PROTEIN / ASIC1 / Modulation / MEMBRANE PROTEIN

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