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TitleCharacterization of class II fumarase from Schistosoma mansoni provides the molecular basis for selective inhibition.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 175, Page 406-421, Year 2021
Publish dateAug 26, 2019 (structure data deposition date)
AuthorsCardoso, I.A. / de Souza, A.K.L. / Burgess, A.M.G. / Chalmers, I.W. / Hoffmann, K.F. / Nonato, M.C.
External linksInt. J. Biol. Macromol. / PubMed:33549669
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-6u4o:
Crystal structure of recombinant class II fumarase from Schistosoma mansoni
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • schistosoma mansoni (invertebrata)
KeywordsLYASE / SmFHII / fumarate hydratase

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