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Structure paper

TitleStructure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli.
Journal, issue, pagesNucleic Acids Res., Vol. 49, Page 2141-2160, Year 2021
Publish dateJun 2, 2020 (structure data deposition date)
AuthorsKopina, B.J. / Missoury, S. / Collinet, B. / Fulton, M.G. / Cirio, C. / van Tilbeurgh, H. / Lauhon, C.T.
External linksNucleic Acids Res. / PubMed:33524148
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-6z81:
TsaBD bound to the inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-QCB:
(2~{S},3~{R})-2-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]ethanoylamino]-3-oxidanyl-butanoic acid

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsRNA BINDING PROTEIN / tRNA TsaB TsaD

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