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Structure paper

TitleAPE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling.
Journal, issue, pagesNat Commun, Vol. 12, Page 601-601, Year 2021
Publish dateJun 18, 2020 (structure data deposition date)
AuthorsLiu, T.C. / Lin, C.T. / Chang, K.C. / Guo, K.W. / Wang, S. / Chu, J.W. / Hsiao, Y.Y.
External linksNat Commun / PubMed:33504804
MethodsX-ray diffraction
Resolution2.7 - 2.701 Å
Structure data

PDB-7cd5:
mAPE1-blunt-ended dsDNA product complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-7cd6:
mAPE1-recessed dsDNA product complex
Method: X-RAY DIFFRACTION / Resolution: 2.701 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / APE1 / protein-nucleic acid interaction / exonuclease / DNA repair / DNA BINDING PROTEIN / HYDROLASE-DNA complex

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