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TitleA High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
Journal, issue, pagesJ. Med. Chem., Vol. 64, Page 1423-1434, Year 2021
Publish dateAug 29, 2018 (structure data deposition date)
AuthorsHaugaard-Kedstrom, L.M. / Clemmensen, L.S. / Sereikaite, V. / Jin, Z. / Fernandes, E.F.A. / Wind, B. / Abalde-Gil, F. / Daberger, J. / Vistrup-Parry, M. / Aguilar-Morante, D. ...Haugaard-Kedstrom, L.M. / Clemmensen, L.S. / Sereikaite, V. / Jin, Z. / Fernandes, E.F.A. / Wind, B. / Abalde-Gil, F. / Daberger, J. / Vistrup-Parry, M. / Aguilar-Morante, D. / Leblanc, R. / Egea-Jimenez, A.L. / Albrigtsen, M. / Jensen, K.E. / Jensen, T.M.T. / Ivarsson, Y. / Vincentelli, R. / Hamerlik, P. / Andersen, J.H. / Zimmermann, P. / Lee, W. / Stromgaard, K.
External linksJ. Med. Chem. / PubMed:33502198
MethodsX-ray diffraction
Resolution1.868 Å
Structure data

PDB-6ak2:
Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018
Method: X-RAY DIFFRACTION / Resolution: 1.868 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • synthetic construct (others)
KeywordsSIGNALING PROTEIN/INHIBITOR / Signaling protein / SIGNALING PROTEIN-INHIBITOR complex

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