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Structure paper

TitleStructure of an inactive conformation of GTP-bound RhoA GTPase.
Journal, issue, pagesStructure, Vol. 29, Page 553-563.e5, Year 2021
Publish dateDec 5, 2019 (structure data deposition date)
AuthorsLin, Y. / Lu, S. / Zhang, J. / Zheng, Y.
External linksStructure / PubMed:33497604
MethodsX-ray diffraction
Resolution1.16 - 1.4 Å
Structure data

PDB-6v6m:
Crystal structure of an inactive state of GMPPNP-bound RhoA
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

PDB-6v6u:
Crystal structure of RhoA-GDP with novel Switch I conformation
Method: X-RAY DIFFRACTION / Resolution: 1.16 Å

PDB-6v6v:
Crystal structure of oncogenic RhoA mutant G14V complexed with GDP
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-DIO:
1,4-DIETHYLENE DIOXIDE

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / GTPase / Switch I / Switch II

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