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TitleMustards-Derived Terpyridine-Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination.
Journal, issue, pagesInorg. Chem., Vol. 60, Page 2414-2424, Year 2021
Publish dateMay 9, 2020 (structure data deposition date)
AuthorsAdams, M. / Sullivan, M.P. / Tong, K.K.H. / Goldstone, D.C. / Hanif, M. / Jamieson, S.M.F. / Hartinger, C.G.
External linksInorg. Chem. / PubMed:33497565
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-6wx5:
Adducts formed after 3 weeks in the reaction of chlorido[chlorido(2,2'-((2-([2,2':6',2''-Terpyridin]-4'-yloxy)ethyl)azanediyl)bis(ethan-1-ol))platinum(II)] with HEWL
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-PT:
Unknown entry

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / metal-based / anticancer / platinum / Terpyridine / lysozyme / metallodrug

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