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TitleNanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Journal, issue, pagesBiochem. J., Vol. 478, Page 579-595, Year 2021
Publish dateOct 26, 2020 (structure data deposition date)
AuthorsDietrich, M.H. / Chan, L.J. / Adair, A. / Keremane, S. / Pymm, P. / Lo, A.W. / Cao, Y.C. / Tham, W.H.
External linksBiochem. J. / PubMed:33480416
MethodsX-ray diffraction
Resolution2 - 3.25 Å
Structure data

PDB-7kj7:
Plasmodium falciparum protein Pf12p
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-7kjh:
Plasmodium falciparum protein Pf12p bound to nanobody B9
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7kji:
Plasmodium falciparum protein Pf12p bound to nanobody D9
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FLC:
CITRATE ANION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • vicugna pacos (alpaca)
KeywordsUNKNOWN FUNCTION / Plasmodium falciparum / 6-cysteine protein / s48/45 domain / nanobody

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