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Structure paper

TitleMechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase beta.
Journal, issue, pagesBiochemistry, Vol. 60, Page 373-380, Year 2021
Publish dateSep 28, 2020 (structure data deposition date)
AuthorsVarela, F.A. / Freudenthal, B.D.
External linksBiochemistry / PubMed:33475337
MethodsX-ray diffraction
Resolution2.1 - 2.4 Å
Structure data

PDB-7k96:
Human DNA polymerase beta ternary complex with templating cytosine and incoming deoxyguanosine diphosphate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7k97:
Human DNA polymerase beta dGDP product complex with Mn2+
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CA:
Unknown entry

ChemComp-DGI:
2'-DEOXYGUANOSINE-5'-DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / DNA repair / polymerase / DNA BINDING PROTEIN / TRANSFERASE-DNA complex / nucleotide analog

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