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Title | Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. |
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Journal, issue, pages | Immunity, Vol. 54, Page 324-339.e8, Year 2021 |
Publish date | Jul 28, 2020 (structure data deposition date) |
Authors | Chen, X. / Zhou, T. / Schmidt, S.D. / Duan, H. / Cheng, C. / Chuang, G.Y. / Gu, Y. / Louder, M.K. / Lin, B.C. / Shen, C.H. ...Chen, X. / Zhou, T. / Schmidt, S.D. / Duan, H. / Cheng, C. / Chuang, G.Y. / Gu, Y. / Louder, M.K. / Lin, B.C. / Shen, C.H. / Sheng, Z. / Zheng, M.X. / Doria-Rose, N.A. / Joyce, M.G. / Shapiro, L. / Tian, M. / Alt, F.W. / Kwong, P.D. / Mascola, J.R. |
External links | Immunity / PubMed:33453152 |
Methods | X-ray diffraction |
Resolution | 2.75 - 3.45 Å |
Structure data | PDB-7jks: PDB-7jkt: |
Chemicals | ChemComp-NAG: ChemComp-HOH: ChemComp-EPE: ChemComp-SO4: |
Source |
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Keywords | IMMUNE SYSTEM / broadly neutralizing antibody / VRC01-class / vaccine-elicited / HIV-1 / Viral Protein/Immune System / Viral Protein-Immune System complex |