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-Structure paper
Title | LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency. |
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Journal, issue, pages | Nucleic Acids Res., Vol. 49, Page 1619-1630, Year 2021 |
Publish date | Dec 17, 2020 (structure data deposition date) |
![]() | Jurkiw, T.J. / Tumbale, P.P. / Schellenberg, M.J. / Cunningham-Rundles, C. / Williams, R.S. / O'Brien, P.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.901 - 2 Å |
Structure data | ![]() PDB-7l34: ![]() PDB-7l35: |
Chemicals | ![]() ChemComp-AMP: ![]() ChemComp-HOH: ![]() ChemComp-PEG: ![]() ChemComp-NA: ![]() ChemComp-TRS: |
Source |
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![]() | LIGASE/DNA / DNA Ligase / LIGASE / LIGASE-DNA complex |