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Structure paper

TitleA phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Journal, issue, pagesMol. Cell, Vol. 81, Page 571-583.e6, Year 2021
Publish dateDec 9, 2019 (structure data deposition date)
AuthorsShah, M. / Taylor, V.L. / Bona, D. / Tsao, Y. / Stanley, S.Y. / Pimentel-Elardo, S.M. / McCallum, M. / Bondy-Denomy, J. / Howell, P.L. / Nodwell, J.R. ...Shah, M. / Taylor, V.L. / Bona, D. / Tsao, Y. / Stanley, S.Y. / Pimentel-Elardo, S.M. / McCallum, M. / Bondy-Denomy, J. / Howell, P.L. / Nodwell, J.R. / Davidson, A.R. / Moraes, T.F. / Maxwell, K.L.
External linksMol. Cell / PubMed:33412111
MethodsX-ray diffraction
Resolution2.08 - 3 Å
Structure data

PDB-6v7u:
Structure of a phage-encoded quorum sensing anti-activator, Aqs1
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-6v7v:
Structure of a phage-encoded quorum sensing anti-activator, Aqs1
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6v7w:
Crystal structure of LasR-Aqs1 complex from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6v7x:
Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-OHN:
N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE

Source
  • pseudomonas virus dms3
  • pseudomonas aeruginosa (strain ucbpp-pa14) (bacteria)
KeywordsVIRAL PROTEIN / Prophage protein / DNA BINDING PROTEIN/Viral protein / quorum sensing / DNA BINDING PROTEIN / DNA BINDING PROTEIN-Viral protein complex

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