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Structure paper

TitleStructure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein.
Journal, issue, pagesMsphere, Vol. 6, Year 2021
Publish dateAug 27, 2019 (structure data deposition date)
AuthorsBarber, N.M. / Lau, C.K.Y. / Turner, L. / Watson, G. / Thrane, S. / Lusingu, J.P.A. / Lavstsen, T. / Higgins, M.K.
External linksMsphere / PubMed:33408232
MethodsX-ray diffraction
Resolution3.11 Å
Structure data

PDB-6sny:
Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR
Method: X-RAY DIFFRACTION / Resolution: 3.11 Å

Chemicals

ChemComp-PTY:
PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / PfEMP1 EPCR vaccine immunogen

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