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TitleStructural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Journal, issue, pagesNucleic Acids Res., Vol. 49, Page 568-583, Year 2021
Publish dateMay 14, 2020 (structure data deposition date)
AuthorsGao, Y. / Liu, H. / Zhang, C. / Su, S. / Chen, Y. / Chen, X. / Li, Y. / Shao, Z. / Zhang, Y. / Shao, Q. ...Gao, Y. / Liu, H. / Zhang, C. / Su, S. / Chen, Y. / Chen, X. / Li, Y. / Shao, Z. / Zhang, Y. / Shao, Q. / Li, J. / Huang, Z. / Ma, J. / Gan, J.
External linksNucleic Acids Res. / PubMed:33332555
MethodsX-ray diffraction
Resolution1.769 - 2.3 Å
Structure data

PDB-7c42:
The crystal structure of Trypanosoma brucei RNase D
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7c43:
The crystal structure of Trypanosoma brucei RNase D : AMP complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-7c45:
The crystal structure of Trypanosoma brucei RNase D complex with RNA U12
Method: X-RAY DIFFRACTION / Resolution: 1.769 Å

PDB-7c47:
The crystal structure of Trypanosoma brucei RNase D : CMP complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-7c4b:
The crystal structure of Trypanosoma brucei RNase D : UMP complex
Method: X-RAY DIFFRACTION / Resolution: 2.101 Å

PDB-7c4c:
The crystal structure of Trypanosoma brucei RNase D : GMP complex
Method: X-RAY DIFFRACTION / Resolution: 2.265 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-CA:
Unknown entry

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-U5P:
URIDINE-5'-MONOPHOSPHATE

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

Source
  • trypanosoma brucei brucei (strain 927/4 gutat10.1) (eukaryote)
  • synthetic construct (others)
KeywordsHYDROLASE / Trypanosoma brucei / RNase D / guide RNA degradation / RNA BINDING PROTEIN / AMP / RNA BINDING PROTEIN/RNA / RNA U12 / RNA BINDING PROTEIN-RNA complex / CMP / UMP / GMP

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