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TitleAberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Journal, issue, pagesNat Commun, Vol. 11, Page 6341-6341, Year 2020
Publish dateAug 26, 2019 (structure data deposition date)
AuthorsJutzi, D. / Campagne, S. / Schmidt, R. / Reber, S. / Mechtersheimer, J. / Gypas, F. / Schweingruber, C. / Colombo, M. / von Schroetter, C. / Loughlin, F.E. ...Jutzi, D. / Campagne, S. / Schmidt, R. / Reber, S. / Mechtersheimer, J. / Gypas, F. / Schweingruber, C. / Colombo, M. / von Schroetter, C. / Loughlin, F.E. / Devoy, A. / Hedlund, E. / Zavolan, M. / Allain, F.H. / Ruepp, M.D.
External linksNat Commun / PubMed:33311468
MethodsNMR (solution)
Structure data

PDB-6snj:
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsSPLICING / Splicing regulation / FUS-U1snRNP / Spliceosome

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