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TitleCrystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 32402-32412, Year 2020
Publish dateJan 9, 2020 (structure data deposition date)
AuthorsZhang, P. / Azizi, L. / Kukkurainen, S. / Gao, T. / Baikoghli, M. / Jacquier, M.C. / Sun, Y. / Maatta, J.A.E. / Cheng, R.H. / Wehrle-Haller, B. ...Zhang, P. / Azizi, L. / Kukkurainen, S. / Gao, T. / Baikoghli, M. / Jacquier, M.C. / Sun, Y. / Maatta, J.A.E. / Cheng, R.H. / Wehrle-Haller, B. / Hytonen, V.P. / Wu, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:33288722
MethodsX-ray diffraction
Resolution2.78 Å
Structure data

PDB-6vgu:
Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / talin / FERM-fold / NPLY motif / integrin

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