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-Structure paper
| Title | Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models. |
|---|---|
| Journal, issue, pages | Mol. Cancer Ther., Vol. 20, Page 320-328, Year 2021 |
| Publish date | Jul 17, 2020 (structure data deposition date) |
Authors | Moquist, P.N. / Bovee, T.D. / Waight, A.B. / Mitchell, J.A. / Miyamoto, J.B. / Mason, M.L. / Emmerton, K.K. / Stevens, N. / Balasubramanian, C. / Simmons, J.K. ...Moquist, P.N. / Bovee, T.D. / Waight, A.B. / Mitchell, J.A. / Miyamoto, J.B. / Mason, M.L. / Emmerton, K.K. / Stevens, N. / Balasubramanian, C. / Simmons, J.K. / Lyon, R.P. / Senter, P.D. / Doronina, S.O. |
External links | Mol. Cancer Ther. / PubMed:33288628 |
| Methods | X-ray diffraction |
| Resolution | 2.35 Å |
| Structure data | ![]() PDB-7jfr: |
| Chemicals | ![]() ChemComp-GTP: ![]() ChemComp-MG: ![]() ChemComp-CA: ![]() ChemComp-GDP: ![]() ChemComp-ACP: ![]() ChemComp-HOH: |
| Source |
|
Keywords | CELL CYCLE / Auristatin / Tubulin / Antimitotic |
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