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Structure paper

TitleInsulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Journal, issue, pagesProtein Sci., Vol. 30, Page 485-496, Year 2021
Publish dateJun 2, 2020 (structure data deposition date)
AuthorsJohansson, E. / Wu, X. / Yu, B. / Yang, Z. / Cao, Z. / Wiberg, C. / Jeppesen, C.B. / Poulsen, F.
External linksProtein Sci. / PubMed:33277949
MethodsX-ray diffraction
Resolution2.15 - 2.42 Å
Structure data

PDB-6z7w:
Human insulin in complex with the analytical antibody HUI-018 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-6z7x:
Insulin analytical antibody OXI-005 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-6z7y:
Human insulin in complex with the analytical antibody OXI-005 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6z7z:
Porcine insulin in complex with the analytical antibody OXI-005 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
  • sus scrofa (pig)
KeywordsHORMONE / complex / insulin / analytical antibody / Fab / PROTEIN BINDING

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