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Title | A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton. |
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Journal, issue, pages | Cell Chem Biol, Vol. 28, Page 228-, Year 2021 |
Publish date | Jul 28, 2020 (structure data deposition date) |
Authors | Gao, L. / Meiring, J.C.M. / Kraus, Y. / Wranik, M. / Weinert, T. / Pritzl, S.D. / Bingham, R. / Ntouliou, E. / Jansen, K.I. / Olieric, N. ...Gao, L. / Meiring, J.C.M. / Kraus, Y. / Wranik, M. / Weinert, T. / Pritzl, S.D. / Bingham, R. / Ntouliou, E. / Jansen, K.I. / Olieric, N. / Standfuss, J. / Kapitein, L.C. / Lohmuller, T. / Ahlfeld, J. / Akhmanova, A. / Steinmetz, M.O. / Thorn-Seshold, O. |
External links | Cell Chem Biol / PubMed:33275880 |
Methods | X-ray diffraction |
Resolution | 1.747 - 2.04 Å |
Structure data | PDB-6zwb: PDB-6zwc: |
Chemicals | ChemComp-GTP: ChemComp-MG: ChemComp-GDP: ChemComp-QRN: ChemComp-HOH: ChemComp-QRQ: |
Source |
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Keywords | CELL CYCLE / photopharmacology / microtubule dynamics / cytoskeleton / tubulin polymerisation inhibitor / colchicine / antimitotic / azobenzene / cell division / spatiotemporal control |