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-Structure paper
Title | Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 142, Page 21178-21188, Year 2020 |
Publish date | Jul 2, 2020 (structure data deposition date) |
Authors | Krumpe, L.R.H. / Wilson, B.A.P. / Marchand, C. / Sunassee, S.N. / Bermingham, A. / Wang, W. / Price, E. / Guszczynski, T. / Kelley, J.A. / Gustafson, K.R. ...Krumpe, L.R.H. / Wilson, B.A.P. / Marchand, C. / Sunassee, S.N. / Bermingham, A. / Wang, W. / Price, E. / Guszczynski, T. / Kelley, J.A. / Gustafson, K.R. / Pommier, Y. / Rosengren, K.J. / Schroeder, C.I. / O'Keefe, B.R. |
External links | J. Am. Chem. Soc. / PubMed:33263997 |
Methods | NMR (solution) |
Structure data | PDB-6xn9: |
Source |
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Keywords | TOXIN / cystine-rich peptide / protein knot / tyrosyl-DNA Phosphodiesterase I inhibitor / marine natural product |