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TitleSolution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051.
Journal, issue, pagesProtein Sci., Vol. 30, Page 448-463, Year 2021
Publish dateMar 25, 2019 (structure data deposition date)
AuthorsChen, C.Y. / Lee, W. / Renhowe, P.A. / Jung, J. / Montfort, W.R.
External linksProtein Sci. / PubMed:33236796
MethodsNMR (solution)
Structure data

PDB-6ocv:
Solution structure of the H-NOX protein from Shewanella woodyi in the Fe(II)CO ligation state
Method: SOLUTION NMR

PDB-6wqe:
Solution Structure of the IWP-051-bound H-NOX from Shewanella woodyi in the Fe(II)CO ligation state
Method: SOLUTION NMR

Chemicals

ChemComp-CMO:
CARBON MONOXIDE

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-IWP:
5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-ol

Source
  • shewanella woodyi (bacteria)
KeywordsSIGNALING PROTEIN / hemoprotein / nitric oxide / signaling / sGC stimulator Complex

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