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-Structure paper
Title | Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 14740-14760, Year 2020 |
Publish date | Sep 26, 2020 (structure data deposition date) |
Authors | Sun, L.Q. / Mull, E. / D'Andrea, S. / Zheng, B. / Hiebert, S. / Gillis, E. / Bowsher, M. / Kandhasamy, S. / Baratam, V.R. / Puttaswamy, S. ...Sun, L.Q. / Mull, E. / D'Andrea, S. / Zheng, B. / Hiebert, S. / Gillis, E. / Bowsher, M. / Kandhasamy, S. / Baratam, V.R. / Puttaswamy, S. / Pulicharla, N. / Vishwakrishnan, S. / Reddy, S. / Trivedi, R. / Sinha, S. / Sivaprasad, S. / Rao, A. / Desai, S. / Ghosh, K. / Anumula, R. / Kumar, A. / Rajamani, R. / Wang, Y.K. / Fang, H. / Mathur, A. / Rampulla, R. / Zvyaga, T.A. / Mosure, K. / Jenkins, S. / Falk, P. / Tagore, D.M. / Chen, C. / Rendunchintala, K. / Loy, J. / Meanwell, N.A. / McPhee, F. / Scola, P.M. |
External links | J. Med. Chem. / PubMed:33226226 |
Methods | X-ray diffraction |
Resolution | 2.15 Å |
Structure data | PDB-7d5l: |
Chemicals | ChemComp-ZN: ChemComp-GXO: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN / NS3/4A Protease |