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TitleStructural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1.
Journal, issue, pagesStructure, Vol. 29, Page 226-237.e4, Year 2021
Publish dateSep 29, 2020 (structure data deposition date)
AuthorsYelland, T. / Le, A.H. / Nikolaou, S. / Insall, R. / Machesky, L. / Ismail, S.
External linksStructure / PubMed:33217330
MethodsX-ray diffraction
Resolution2.37 - 3.1 Å
Structure data

PDB-7ajk:
Crystal structure of CRYI-B Rac1 complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-7ajl:
Cyrstal structure of CYRI-B/Fam49B
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsCYTOSOLIC PROTEIN / Actin / cytoskeleton / Rac1 / GTPase / Inhibitor / Rac1 competitor / actin regulation / Scar/WAVE inhibitor

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