+Search query
-Structure paper
Title | Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 63, Page 14724-14739, Year 2020 |
Publish date | Jun 11, 2020 (structure data deposition date) |
Authors | Pagare, P.P. / Ghatge, M.S. / Chen, Q. / Musayev, F.N. / Venitz, J. / Abdulmalik, O. / Zhang, Y. / Safo, M.K. |
External links | J. Med. Chem. / PubMed:33205981 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | PDB-6xdt: PDB-6xe7: |
Chemicals | ChemComp-CMO: ChemComp-HEM: ChemComp-V1M: ChemComp-HOH: ChemComp-V2D: |
Source |
|
Keywords | OXYGEN TRANSPORT / Hemoglobin / Aromatic aldehyde / Antisickling / Allosteric effector |