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-Structure paper
| Title | Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 11, Page 5861-5861, Year 2020 |
| Publish date | May 19, 2020 (structure data deposition date) |
Authors | Cicconi, A. / Rai, R. / Xiong, X. / Broton, C. / Al-Hiyasat, A. / Hu, C. / Dong, S. / Sun, W. / Garbarino, J. / Bindra, R.S. ...Cicconi, A. / Rai, R. / Xiong, X. / Broton, C. / Al-Hiyasat, A. / Hu, C. / Dong, S. / Sun, W. / Garbarino, J. / Bindra, R.S. / Schildkraut, C. / Chen, Y. / Chang, S. |
External links | Nat Commun / PubMed:33203878 |
| Methods | X-ray diffraction |
| Resolution | 2.151 Å |
| Structure data | ![]() PDB-7c5d: |
| Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
| Source |
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Keywords | PROTEIN BINDING / Telomere / shelterin complex / TRF2 / MCPH1 / DNA repair |
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homo sapiens (human)
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