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-Structure paper
| タイトル | Structural insights into the photoactivation of Arabidopsis CRY2. |
|---|---|
| ジャーナル・号・ページ | Nat Plants, Vol. 6, Issue 12, Page 1432-1438, Year 2020 |
| 掲載日 | 2020年11月16日 |
著者 | Ling Ma / Zeyuan Guan / Qiang Wang / Xuhui Yan / Jing Wang / Zhizheng Wang / Jianbo Cao / Delin Zhang / Xin Gong / Ping Yin / ![]() |
| PubMed 要旨 | The blue-light receptor cryptochrome (CRY) in plants undergoes oligomerization to transduce blue-light signals after irradiation, but the corresponding molecular mechanism remains poorly understood. ...The blue-light receptor cryptochrome (CRY) in plants undergoes oligomerization to transduce blue-light signals after irradiation, but the corresponding molecular mechanism remains poorly understood. Here, we report the cryogenic electron microscopy structure of a blue-light-activated CRY2 tetramer at a resolution of 3.1 Å, which shows how the CRY2 tetramer assembles. Our study provides insights into blue-light-mediated activation of CRY2 and a theoretical basis for developing regulators of CRYs for optogenetic manipulation. |
リンク | Nat Plants / PubMed:33199893 |
| 手法 | EM (単粒子) |
| 解像度 | 3.1 Å |
| 構造データ | EMDB-30128, PDB-6m79: |
| 化合物 | ![]() ChemComp-AMP: ![]() ChemComp-FAD: |
| 由来 |
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キーワード | TRANSCRIPTION / blue-light activated / Arabidopsis thaliana / CRY2 tetramer |
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