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-Structure paper
| Title | Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers. |
|---|---|
| Journal, issue, pages | Life Sci Alliance, Vol. 4, Year 2021 |
| Publish date | Mar 30, 2020 (structure data deposition date) |
Authors | Newman, J.A. / Gavard, A.E. / Lieb, S. / Ravichandran, M.C. / Hauer, K. / Werni, P. / Geist, L. / Bottcher, J. / Engen, J.R. / Rumpel, K. ...Newman, J.A. / Gavard, A.E. / Lieb, S. / Ravichandran, M.C. / Hauer, K. / Werni, P. / Geist, L. / Bottcher, J. / Engen, J.R. / Rumpel, K. / Samwer, M. / Petronczki, M. / Gileadi, O. |
External links | Life Sci Alliance / PubMed:33199508 |
| Methods | X-ray diffraction |
| Resolution | 2.2 Å |
| Structure data | ![]() PDB-6yhr: |
| Chemicals | ![]() ChemComp-ADP: ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
| Source |
|
Keywords | HYDROLASE / Helicase / Werners syndrome / DNA repair |
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homo sapiens (human)
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