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TitleSalivary complement inhibitors from mosquitoes: Structure and mechanism of action.
Journal, issue, pagesJ. Biol. Chem., Vol. 296, Page 100083-100083, Year 2020
Publish dateJun 26, 2020 (structure data deposition date)
AuthorsStrayer, E.C. / Lu, S. / Ribeiro, J. / Andersen, J.F.
External linksJ. Biol. Chem. / PubMed:33199367
MethodsX-ray diffraction
Resolution1.42 - 2.31 Å
Structure data

PDB-6xke:
Structure of a mosquito complement inhibitor from Anopheles albimanus
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-6xl7:
Structure of a mosquito complement inhibitor from Anopheles freeborni
Method: X-RAY DIFFRACTION / Resolution: 1.42 Å

PDB-6xmb:
Structure of an anophensin from Anopheles stephensi
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-BR:
BROMIDE ION

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

Source
  • anopheles albimanus (mosquito)
  • anopheles freeborni (western malaria mosquito)
  • anopheles stephensi (Asian malaria mosquito)
KeywordsPROTEIN BINDING / Inhibitor / complement / alternative pathway / C3bBb / contact pathway

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