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TitleCo-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38.
Journal, issue, pagesNat Commun, Vol. 11, Page 5769-5769, Year 2020
Publish dateJul 10, 2020 (structure data deposition date)
AuthorsKirsch, K. / Zeke, A. / Toke, O. / Sok, P. / Sethi, A. / Sebo, A. / Kumar, G.S. / Egri, P. / Poti, A.L. / Gooley, P. ...Kirsch, K. / Zeke, A. / Toke, O. / Sok, P. / Sethi, A. / Sebo, A. / Kumar, G.S. / Egri, P. / Poti, A.L. / Gooley, P. / Peti, W. / Bento, I. / Alexa, A. / Remenyi, A.
External linksNat Commun / PubMed:33188182
MethodsX-ray diffraction
Resolution1.95 - 2.699 Å
Structure data

PDB-6zqs:
Crystal structure of double-phosphorylated p38alpha with ATF2(83-102)
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-6zr5:
Crystal structure of JNK1 in complex with ATF2(19-58)
Method: X-RAY DIFFRACTION / Resolution: 2.699 Å

Chemicals

ChemComp-3FF:
2-[(2,4-difluorophenyl)amino]-7-{[(2R)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / MAPK SIGNALING PATHWAYS

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