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TitleCrystallographic Snapshots of the Dunathan and Quinonoid Intermediates provide Insights into the Reaction Mechanism of Group II Decarboxylases.
Journal, issue, pagesJ. Mol. Biol., Vol. 432, Page 166692-166692, Year 2020
Publish dateMar 9, 2020 (structure data deposition date)
AuthorsGayathri, S.C. / Manoj, N.
External linksJ. Mol. Biol. / PubMed:33122004
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6m4y:
Structure of a R371A mutant of a Group II PLP dependent decarboxylase from Methanocaldococcus jannaschii
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • methanocaldococcus jannaschii (strain atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 100440) (archaea)
KeywordsLYASE / PLP dependent decarboxylase / Catalytic mutant / Protein Conformation / LLP / internal aldimine / Tyrosine / Tyrosine Decarboxylase / Structure-Activity Relationship

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