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-Structure paper
Title | Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response. |
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Journal, issue, pages | Prog. Biophys. Mol. Biol., Vol. 163, Page 130-142, Year 2021 |
Publish date | May 19, 2020 (structure data deposition date) |
![]() | Wilson 3rd, D.M. / Deacon, A.M. / Duncton, M.A.J. / Pellicena, P. / Georgiadis, M.M. / Yeh, A.P. / Arvai, A.S. / Moiani, D. / Tainer, J.A. / Das, D. |
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Methods | X-ray diffraction |
Resolution | 1.9 - 2.35 Å |
Structure data | ![]() PDB-6x1y: ![]() PDB-6x1z: |
Chemicals | ![]() ChemComp-MES: ![]() ChemComp-UKV: ![]() ChemComp-HOH: ![]() ChemComp-UL1: ![]() ChemComp-MG: |
Source |
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![]() | HYDROLASE / DNA REPAIR MRE11 THERMOPHILIC NUCLEASE / DNA DOUBLE-STRAND BREAK REPAIR / HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR complex |