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Structure paper

TitleA far-red cyanobacteriochrome lineage specific for verdins.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 27962-27970, Year 2020
Publish dateJun 18, 2020 (structure data deposition date)
AuthorsMoreno, M.V. / Rockwell, N.C. / Mora, M. / Fisher, A.J. / Lagarias, J.C.
External linksProc. Natl. Acad. Sci. USA / PubMed:33106421
MethodsX-ray diffraction
Resolution1.5 - 2.3 Å
Structure data

PDB-6xhg:
Far-red absorbing dark state of JSC1_58120g3 with bound biliverdin IXa (BV)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6xhh:
Far-red absorbing dark state of JSC1_58120g3 with bound 18-1, 18-2 dihydrobiliverdin IXa (DHBV), the native chromophore precursor
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-BVX:
3-[2-[(~{Z})-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-2-ylidene]methyl]-5-[(~{Z})-(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-M1V:
mesobiliverdin IX(alpha)

Source
  • [leptolyngbya] sp. jsc-1 (bacteria)
KeywordsSIGNALING PROTEIN / Cyanobacteriochrome GAF Domain Phytochrome superfamily Biliverdin / Cyanobacteriochrome GAF Domain Phytochrome-superfamily 18-1 / 18-2 Dihydrobiliverdin

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