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TitleNeuropilin-1 is a host factor for SARS-CoV-2 infection.
Journal, issue, pagesScience, Vol. 370, Page 861-865, Year 2020
Publish dateJul 25, 2020 (structure data deposition date)
AuthorsDaly, J.L. / Simonetti, B. / Klein, K. / Chen, K.E. / Williamson, M.K. / Anton-Plagaro, C. / Shoemark, D.K. / Simon-Gracia, L. / Bauer, M. / Hollandi, R. ...Daly, J.L. / Simonetti, B. / Klein, K. / Chen, K.E. / Williamson, M.K. / Anton-Plagaro, C. / Shoemark, D.K. / Simon-Gracia, L. / Bauer, M. / Hollandi, R. / Greber, U.F. / Horvath, P. / Sessions, R.B. / Helenius, A. / Hiscox, J.A. / Teesalu, T. / Matthews, D.A. / Davidson, A.D. / Collins, B.M. / Cullen, P.J. / Yamauchi, Y.
External linksScience / PubMed:33082294
MethodsX-ray diffraction
Resolution2.36 Å
Structure data

PDB-7jjc:
Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsSIGNALING PROTEIN / Neuropilin-1 / receptor binding / Coronavirus / SARS-CoV-2 / spike protein

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