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TitleAn Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.
Journal, issue, pagesBiochemistry, Vol. 59, Page 4163-4175, Year 2020
Publish dateNov 14, 2019 (structure data deposition date)
AuthorsSingh, N.K. / Alonso, J.A. / Harris, D.T. / Anderson, S.D. / Ma, J. / Hellman, L.M. / Rosenberg, A.M. / Kolawole, E.M. / Evavold, B.D. / Kranz, D.M. / Baker, B.M.
External linksBiochemistry / PubMed:33074657
MethodsX-ray diffraction
Resolution3.14 Å
Structure data

PDB-6uz1:
Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2
Method: X-RAY DIFFRACTION / Resolution: 3.14 Å

Chemicals

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / single-chain T cell receptor / peptide Major Histocompatibility complex

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