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TitleTargeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits.
Journal, issue, pagesJ. Pharmacol. Exp. Ther., Vol. 375, Page 510-521, Year 2020
Publish dateJul 7, 2020 (structure data deposition date)
AuthorsSun, W. / Zhang, X. / Cummings, M.D. / Albarazanji, K. / Wu, J. / Wang, M. / Alexander, R. / Zhu, B. / Zhang, Y. / Leonard, J. ...Sun, W. / Zhang, X. / Cummings, M.D. / Albarazanji, K. / Wu, J. / Wang, M. / Alexander, R. / Zhu, B. / Zhang, Y. / Leonard, J. / Lanter, J. / Lenhard, J.
External linksJ. Pharmacol. Exp. Ther. / PubMed:33033171
MethodsX-ray diffraction
Resolution2.19 Å
Structure data

PDB-6zov:
ENTEROPEPTIDASE IN COMPLEX WITH COMPOUND 6
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-GBS:
4-carbamimidamidobenzoic acid

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PEPTIDASE

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